Srv mediated dispersal of streptococcal biofilms through SpeB is observed in CovRS+ strains.
Group A Streptococcus (GAS) is a human specific pathogen capable of causing both mild infections and severe invasive disease.We and others have shown that GAS is able to form biofilms during infection.That is to say, they form a Cardamon three-dimensional, surface attached structure consisting of bacteria and a multi-component extracellular matrix.